参考文献

[1]杨惠玲.细胞增殖和凋亡异常与疾病//金惠铭.病理生理学.北京:人民卫生出版社,2013:141-151.
[2]龚建平.细胞周期与肿瘤发生、发展//曾盖新.肿瘤学.北京:人民卫生出版社,2014:122-126.
[3]Zhou Y,Shen JK,Hornicek FJ,et al.The Emerging Roles and Therapeutic Potential of Cyclin-Dependent Kinase 11(Cdk11)in Human Cancer.Oncotarget,2016,7(26):40846-40859.
[4]Liang K,Gao X,Gilmore JM,et al.Characterization of Human Cyclin-Dependent Kinase 12(Cdk12)and Cdk13 Complexes in C-Terminal Domain Phosphorylation,Gene Transcription,and Rna Processing.Mol Cell Biol,2015,35(6):928-938.
[5]Chila R,Guffanti F,Damia G.Role and Therapeutic Potential of Cdk12 in Human Cancers.Cancer Treat Rev,2016,50:83-88.
[6]Even Y,Escande M.,Fayet C,et al.Cdk13,a Kinase Involved in Pre-Mrna Splicing,is a Component of the Perinucleolar Compartment.PLoS One,2016,11 (2):e149184.
[7]Stivala LA,Riva F,Cazzalini O,et al.P21(Waf1/Cip1)-Null Human Fibroblasts are Deficient in Nucleotide Excision Repair Downstream the Recruitment of Pcna to Dna Repair Sites.Oncogene,2001,20(5):563-570.
[8]Lecanda J,Ganapathy V,D’Aquino-Ardalan C,et al.Tgfbeta Prevents Proteasomal Degradation of the Cyclin-Dependent Kinase Inhibitor P27Kip1 for Cell Cycle Arrest.Cell Cycle,2009,8(5):742-756.
[9]Tu Y,Chen C,Pan J,et al.The Ubiquitin Proteasome Pathway(Upp)in the Regulation of Cell Cycle Control and Dna Damage Repair and its Implication in Tumorigenesis.International Journal of Clinical and Experimental Pathology,2012,5(8):726.
[10]Cui H,Zhao C,Gong P,et al.Dna Methyltransferase 3a Promotes Cell Proliferation by Silencing Cdk Inhibitor P18Ink4C in Gastric Carcinogenesis.Sci Rep,2015,5:13781.
[11]Nakayama KI,Nakayama K.Ubiquitin Ligases:Cell-Cycle Control and Cancer.Nat Rev Cancer,2006,6(5):369-381.
[12]He D,Zeng Q,Ren G,et al.Protocadherin8 is a Functional Tumor Suppressor Frequently Inactivated by Promoter Methylation in Nasopharyngeal Carcinoma.European journal of cancer prevention:the official journal of the European Cancer Prevention Organisation(ECP),2012,21(6):569.
[13]张颖.Cyclind1、Cdk4及P16在糖尿病早期肾脏细胞的表达.河北医科大学,硕士,2003:53.
[14]Taniguchi Y,Pippin JW,Hagmann H,et al Both Cyclin I and P35 are Required for Maximal Survival Benefit of Cyclin-Dependent Kinase 5 in Kidney Podocytes.Am J Physiol Renal Physiol,2012,302(9):F1161-F1171.
[15]Parrales A,Iwakuma T.Targeting Oncogenic Mutant P53 for Cancer Therapy.Front Oncol,2015,5:288.
[16]Zhang R,Wang H,Agrawal S.Novel Antisense Anti-Mdm2 Mixed-Backbone Oligonucleotides:Proof of Principle,in Vitro and in Vivo Activities,and Mechanisms.Curr Cancer Drug Targets,2005,5(1):43-49.
[17]刘斌,高英茂.人体胚胎学.北京:人民卫生出版社,1996.
[18]杨洋,文继红.卵巢恶性畸胎瘤研究进展.吉林医学,2010,4:543-545.
[19]Greene Nd CA.Neural-Tube Defects.Annu Rev Neurosci,2014,341(37):221-242.
[20]Srivastava D.Making Or Breaking the Heart:From Lineage Determination to Morphogenesis.Cell,2006,6(126):1037-1048.
[21]吴德沛.白血病//葛均波,徐永健.内科学.北京:人民卫生出版社,2013:578-592.
[22]陈国强.细胞分化和肿瘤//肿瘤学.北京:人民卫生出版社,2014:129-135.
[23]Chen Z,Breitman TR.Effects of Prostaglandin E2 and All-Trans Retinoic Acid Combination On Induced Differentiation of Human Acute Promyelocytic Leukemia Nb4 Cells.Chin Med J(Engl),1997,110(10):783-788.
[24]Soignet SL,Frankel SR,Douer D,et al.United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia.J Clin Oncol,2001,19(18):3852-3860.